ABSTRACT
SESSION TITLE: COPD Assessment Tools and Comorbidities SESSION TYPE: Rapid Fire Original Inv PRESENTED ON: 10/17/2022 12:15 pm - 1:15 pm PURPOSE: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common cause of hospital admissions. Coronavirus disease 2019 (COVID-19) has large impact on patients with pulmonary diseases. The purpose of the study is to evaluate the impact of COVID-19 on the following parameters for patients with COPD: Admission rate, length of stay, need for mechanical ventilation and all-cause mortality METHODS: Retrospective study with two cohorts, the first period is for patients admitted to the hospital with AECOPD before COVID-19 pandemic (01/01/2019 to 12/30/2019);the second period is for patients admitted with AECOPD since the beginning of COVID-19 pandemic (4/1/2020 to 3/31/2021). The length of stay (LOS), rate of patients requiring mechanical ventilation, and all-cause mortality were calculated and compared between two-groups of age, gender and comorbidities. RESULTS: There was a total of 55 (44.72%) patients in the pre-COVID period compared to 68 (55.28%) patients in the post-COVID period. In the pre-COVID period 16 (29.09%) patients were less than 60 year old and 39 (44.83%) patients were more than 60 year old. In the post-COVID period 39 (70.91%) patients were less than 60 year old and 48 (55.17%) patients were more than 60 year old. As for patients’ comorbidities, in pre-COVID period: 14 (19.44%) had hypertension, 26(36.11%) had diabetes, 27(37.50%) had ischemic heart disease, 3(4.17%) had myocardial infarction;in the post-COVID period: 20 (29.41%) had hypertension, 24(35.29%) had diabetes, 27(39.71%) had ischemic heart disease, 1(1.47) had myocardial infarction. The LOS was shorter in pre-COVID period compared to post-COVID period 6.51(SD 5.02) days vs 8.91(SD7.88) days with P-value of 0.042. The total number of patients needing mechanical ventilation in pre-COVID period was 3 (5.45%) compared to 3 (4.41%) in the post-COVID period with P-value of 0.555. All-cause mortality was 2 (3.64%) compared to 6 (8.82%) in post-COVID period with P-value of 0.217. CONCLUSIONS: Study result revealed significant difference in length of stay for patient with AECOPD where patient in post-COVID period had increased LOS compared to pre-COVID period. There was no significant difference in the number of patients, patients needing mechanical ventilation and all-cause mortality in between the two periods. CLINICAL IMPLICATIONS: The LOS in AECOPD is affected by multiple factors including underlying comorbidities, triggering factors for AECOPD and patient characteristics. Understanding these factors may help to optimize both patient care and health care utilization. Further studies are needed to assess the impact of COVID-19 on use of health care utilization for chronic pulmonary conditions such as COPD. DISCLOSURES: No relevant relationships by Omar Abdulfattah No relevant relationships by Zainab Alnafoosi No relevant relationships by Akshay Kohli No relevant relationships by Peter White